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Literature summary for 4.1.1.46 extracted from

  • Subba Rao, P.V.; Moore, K.; Towers, G.H.N.
    o-Pyrocatechuic acid carboxy-lyase from Aspergillus niger (1967), Arch. Biochem. Biophys., 122, 466-473.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
2,3,4-Trihydroxybenzoate
-
Aspergillus niger
2,3-Dimercaptopropanol
-
Aspergillus niger
2,4-Dihydroxybenzoate competitive Aspergillus niger
3-Hydroxyanthranilate
-
Aspergillus niger
AgNO3
-
Aspergillus niger
CdCl2
-
Aspergillus niger
CuSO4
-
Aspergillus niger
cysteine
-
Aspergillus niger
FeCl3
-
Aspergillus niger
FeSO4
-
Aspergillus niger
HgCl2
-
Aspergillus niger
iodoacetate
-
Aspergillus niger
Mercapotoethanol weak Aspergillus niger
NEM weak Aspergillus niger
o-phenanthroline 1 mM, 50% inactivation Aspergillus niger
PCMB
-
Aspergillus niger
reduced glutathione
-
Aspergillus niger
salicylate competitive Aspergillus niger

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.3
-
2,3-Dihydroxybenzoate
-
Aspergillus niger

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2,3-Dihydroxybenzoate Aspergillus niger enzyme is involved in the biosynthesis of catechol ?
-
?

Organism

Organism UniProt Comment Textmining
Aspergillus niger
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
Aspergillus niger

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
22
-
-
Aspergillus niger

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,3-Dihydroxybenzoate
-
Aspergillus niger Catechol + CO2
-
?
2,3-Dihydroxybenzoate enzyme is involved in the biosynthesis of catechol Aspergillus niger ?
-
?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
42
-
-
Aspergillus niger

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.2
-
-
Aspergillus niger

pH Range

pH Minimum pH Maximum Comment Organism
4.5 7 pH 4.5: about 35% of maximal activity, pH 7.0: about 30% of maximal activity Aspergillus niger

Cofactor

Cofactor Comment Organism Structure
additional information the enzyme does not contain a prosthetic group Aspergillus niger