BRENDA - Enzyme Database
show all sequences of 4.1.1.44

gamma-Carboxymuconolactone decarboxylase A novel cell cycle-related basal body protein in the early branching eukaryote Trichomonas vaginalis

Cheng, W.; Huang, K.; Huang, P.; Lee, C.; Yeh, Y.; Ku, F.; Lin, R.; Cheng, M.; Chiu, C.; Tang, P.; Parasit. Vectors 10, 443 (2017)

Data extracted from this reference:

Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoskeleton
spatially associated with the basal body, a part of the cytoskeletal organizing center
Trichomonas vaginalis
5856
-
Organism
Organism
UniProt
Commentary
Textmining
Trichomonas vaginalis
A2FEX8
-
-
Subunits
Subunits
Commentary
Organism
?
x * 26000, SDS-PAGE
Trichomonas vaginalis
Synonyms
Synonyms
Commentary
Organism
CMD1
-
Trichomonas vaginalis
TVAG_256720
-
Trichomonas vaginalis
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
cytoskeleton
spatially associated with the basal body, a part of the cytoskeletal organizing center
Trichomonas vaginalis
5856
-
Subunits (protein specific)
Subunits
Commentary
Organism
?
x * 26000, SDS-PAGE
Trichomonas vaginalis
Expression
Organism
Commentary
Expression
Trichomonas vaginalis
presence of iron negatively regulates the expression of CMD1
down
Trichomonas vaginalis
expression is not induced by protocatechuate or benzoate
additional information
General Information
General Information
Commentary
Organism
physiological function
CMD1 accumulated upon treatment with the G2/M inhibitor nocodazole. CMD1 is expressed and transported to/from the basal body during cytokinesis, suggesting a role in cell division
Trichomonas vaginalis
General Information (protein specific)
General Information
Commentary
Organism
physiological function
CMD1 accumulated upon treatment with the G2/M inhibitor nocodazole. CMD1 is expressed and transported to/from the basal body during cytokinesis, suggesting a role in cell division
Trichomonas vaginalis
Expression (protein specific)
Organism
Commentary
Expression
Trichomonas vaginalis
presence of iron negatively regulates the expression of CMD1
down
Trichomonas vaginalis
expression is not induced by protocatechuate or benzoate
additional information
Other publictions for EC 4.1.1.44
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Synonyms
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
748826
Cheng
gamma-Carboxymuconolactone de ...
Trichomonas vaginalis
Parasit. Vectors
10
443
2017
-
-
-
-
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
1
1
2
-
-
747316
Yamanashi
In vitro reconstitution of th ...
Rhodococcus jostii
Biosci. Biotechnol. Biochem.
79
830-835
2015
-
-
1
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
701502
Lee
Crystallization and preliminar ...
Saccharolobus solfataricus
Acta Crystallogr. Sect. F
65
1197-1199
2009
-
-
1
1
-
-
-
-
-
-
1
1
-
16
-
-
1
-
-
-
-
-
1
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
1
1
-
-
-
1
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
680482
Hara
Transcriptomic analysis reveal ...
Rhodococcus sp., Rhodococcus sp. RHA1
J. Bacteriol.
189
1641-1647
2007
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
2
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
695732
Buchan
Diverse organization of genes ...
Sulfitobacter pontiacus, Sulfitobacter sp., Ruegeria pomeroyi, Roseovarius nubinhibens ISM, Sagittula stellata E-37, Sulfitobacter pontiacus ChLG 10
Appl. Environ. Microbiol.
70
1658-1668
2004
-
-
2
-
-
-
-
-
-
-
-
6
-
6
-
-
-
-
-
-
-
-
6
-
10
-
-
-
-
2
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
6
-
-
-
-
-
-
-
-
6
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
33102
Eulberg
Characterization of a protocat ...
Rhodococcus opacus, Rhodococcus opacus 1CP
J. Bacteriol.
180
1072-1081
1998
-
-
1
-
-
-
-
-
-
-
-
-
-
12
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2977
Chari
-
Absolute stereochemical course ...
Acinetobacter calcoaceticus, Pseudomonas putida
J. Am. Chem. Soc.
109
5520-5521
1987
-
-
1
-
-
-
-
-
-
-
-
-
-
2
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3668
Doten
Cloning and genetic organizati ...
Acinetobacter calcoaceticus
J. Bacteriol.
169
3168-3174
1987
-
-
-
-
-
-
-
-
-
-
-
1
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3667
Parke
Enzymes of the beta-ketoadipat ...
Agrobacterium tumefaciens, Agrobacterium rhizogenes, Bradyrhizobium japonicum, Bradyrhizobium sp., Sinorhizobium fredii, Rhizobium leguminosarum, Sinorhizobium meliloti
J. Bacteriol.
165
288-292
1986
-
-
-
-
-
-
-
-
-
-
-
7
-
32
-
-
-
-
-
-
-
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
7
-
-
-
-
-
-
-
-
14
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
33103
Yeh
Evolutionary relationships amo ...
Azotobacter vinelandii, Acinetobacter calcoaceticus, Pseudomonas putida
J. Bacteriol.
146
233-238
1981
-
-
-
-
-
-
-
-
-
-
2
-
-
12
-
-
1
-
-
-
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
-
-
1
-
-
2
-
3
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
33104
Yeh
Homologies in the NH2-terminal ...
Acinetobacter calcoaceticus, Pseudomonas putida
J. Biol. Chem.
255
6347-6354
1980
-
-
-
-
-
-
-
-
-
-
4
2
-
11
-
-
2
-
-
-
1
-
4
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
4
2
-
-
-
2
-
-
1
-
4
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
33105
Parke
Relationships among enzymes of ...
Pseudomonas putida
Biochemistry
12
3537-3542
1973
-
-
-
1
-
-
-
-
-
-
-
1
-
5
-
-
1
-
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
1
-
-
-
1
-
-
-
-
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2972
Ornston
-
Conversion of catechol and pro ...
Pseudomonas putida
Methods Enzymol.
17A
529-549
1970
-
-
-
-
-
-
-
1
-
-
1
-
-
1
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
1
-
-
-
-
1
-
-
-
-
-
1
-
-
-
-
-
-
-
-
-