Literature summary for 4.1.1.43 extracted from

Xu, X.; Wang, C.; Chen, J.; Yang, S.
Streptomyces virginiae PPDC is a new type of phenylpyruvate decarboxylase composed of two subunits (2017), ACS Chem. Biol., 12, 2008-2014 .

Search for more literature for 4.1.1.43

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Streptomyces virginiae

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
1.13	-	phenylpyruvate	allosteric enzyme, Hill coefficient 4.7, pH 7.5, temperature not specified in the publication	Streptomyces virginiae

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	required	Streptomyces virginiae

Organism

Organism	UniProt	Comment	Textmining
Streptomyces virginiae	A0A222AKA3	alpha subunit	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Phenylpyruvate	-	Streptomyces virginiae	Phenylacetaldehyde + CO2	-	?

Subunits

Subunits	Comment	Organism
?	x * 41000, alpha-subunit, plus x * 38000, beta-subunit, SDS-PAGE	Streptomyces virginiae

Synonyms

Synonyms	Comment	Organism
PPDC	-	Streptomyces virginiae

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.0055	-	phenylpyruvate	allosteric enzyme, Hill coefficient 4.7, pH 7.5, temperature not specified in the publication	Streptomyces virginiae

Cofactor

Cofactor	Comment	Organism	Structure
thiamine diphosphate	-	Streptomyces virginiae

kcat/KM [mM/s]

kcat/KM Value [1/mMs^-1]	kcat/KM Value Maximum [1/mMs^-1]	Substrate	Comment	Organism	Structure
0.0058	-	phenylpyruvate	allosteric enzyme, Hill coefficient 4.7, pH 7.5, temperature not specified in the publication	Streptomyces virginiae

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Release 2023.1 (January 2023)