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Literature summary for 4.1.1.39 extracted from

  • Burisch, C.; Wildner, G.F.; Schlitter, J.
    Bioinformatic tools uncover the C-terminal strand of Rubiscos large subunit as hot-spot for specificity-enhancing mutations (2007), FEBS Lett., 581, 741-748.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
A340D 5% increase in specificity compared to the wild type enzyme Synechococcus sp.
E470P the mutation loses the internal salt bridge and leads to altered surface electrostatics Synechococcus sp.
K474T the mutation loses the internal salt bridge and leads to altered surface electrostatics Synechococcus sp.

Organism

Organism UniProt Comment Textmining
Synechococcus sp.
-
-
-
Synechococcus sp. PCC6301
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-ribulose 1,5-bisphosphate + CO2 + H2O
-
Synechococcus sp. 3-phospho-D-glycerate
-
?
D-ribulose 1,5-bisphosphate + CO2 + H2O
-
Synechococcus sp. PCC6301 3-phospho-D-glycerate
-
?
D-ribulose 1,5-bisphosphate + O2
-
Synechococcus sp. 3-phospho-D-glycerate + 2-phosphoglycolate
-
?
D-ribulose 1,5-bisphosphate + O2
-
Synechococcus sp. PCC6301 3-phospho-D-glycerate + 2-phosphoglycolate
-
?

Synonyms

Synonyms Comment Organism
Rubisco
-
Synechococcus sp.