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Literature summary for 4.1.1.37 extracted from

  • Billi de Catabbi, S.; Wainstok de Calmanovici, R.; Minutolo, C.; Aldonatti, C.; San Martin de Viale, L.C.
    Porphyria-induced hepatic porphyrinogen carboxy-lyase inhibitor and its interaction with the active site(s) of the enzyme (1999), Biochem. Mol. Biol. Int., 47, 945-956.
    View publication on PubMed
Search for more literature for 4.1.1.37

General Stability

General Stability Organism
4-porphyrinogen protects the enzyme from inhibitor action Rattus norvegicus

Inhibitors

Inhibitors Comment Organism Structure
hexachlorobenzene treatment generated inhibitor
-
 Rattus norvegicus
additional information no inhibition of pentacarboxyporphyrinogen III decarboxylation Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Uroporphyrinogen III Rattus norvegicus heme pathway enzyme, catalyzes the stepwise decarboxylation of porphyrinogen acetic chains Coproporphyrinogen III + 4 CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
 rat, female Wistar
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Uroporphyrinogen III
-
 Rattus norvegicus Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III heme pathway enzyme, catalyzes the stepwise decarboxylation of porphyrinogen acetic chains Rattus norvegicus Coproporphyrinogen III + 4 CO2
-
 ?

Synonyms

Synonyms Comment Organism
PCL
-
 Rattus norvegicus
Porphyrinogen carboxy-lyase
-
 Rattus norvegicus