Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21(DE3) cells | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-fluoromevalonate 5-diphosphate | irreversible inhibitor | Rattus norvegicus | |
geranyl diphosphate | - |
Rattus norvegicus | |
P'-geranyl 2-fluoromevalonate 5-diphosphate | irreversible inhibitor | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00053 | - |
ATP | - |
Rattus norvegicus | |
0.036 | - |
5-diphosphomevalonate | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisome | - |
Rattus norvegicus | 5777 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Rattus norvegicus |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
ATP + 5-diphosphomevalonate | - |
Rattus norvegicus | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MDD | - |
Rattus norvegicus |
Mevalonate 5-diphosphate decarboxylase | - |
Rattus norvegicus |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00302 | - |
2-fluoromevalonate 5-diphosphate | in 100 mM Tris buffer, pH 7.5, at 25°C | Rattus norvegicus | |
0.0046 | - |
P'-geranyl 2-fluoromevalonate 5-diphosphate | in 100 mM Tris buffer, pH 7.5, at 25°C | Rattus norvegicus |