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Literature summary for 4.1.1.28 extracted from

  • Nakazawa, H.
    Decarboxylation reaction of alpha-methyl amino acid catalyzed by aromatic L-amino acid decarboxylase from Micrococcus percitreus (1985), Agric. Biol. Chem., 49, 159-165 .
No PubMed abstract available
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Inhibitors

Inhibitors Comment Organism Structure
alpha-methyl-DL-phenylalanine 76% inhibition at 0.2 mM Micrococcus percitreus
alpha-methyl-DL-tyrosine 71% inhibition at 0.2 mM Micrococcus percitreus
alpha-methyl-L-Dopa 60% inhibition at 0.2 mM Micrococcus percitreus
pyridoxamine phosphate complete inhibition at 0.2 mM Micrococcus percitreus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
2.4
-
 L-tryptophan pH and temperature not specified in the publication Micrococcus percitreus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan Micrococcus percitreus
-
 tryptamine + CO2
-
 ?
L-tryptophan Micrococcus percitreus AJ 1065
-
 tryptamine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Micrococcus percitreus
-
-
-
Micrococcus percitreus AJ 1065
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan
-
 Micrococcus percitreus tryptamine + CO2
-
 ?
L-tryptophan
-
 Micrococcus percitreus AJ 1065 tryptamine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
Aromatic L-amino acid decarboxylase
-
 Micrococcus percitreus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Micrococcus percitreus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
46
-
 alpha-methyl-DL-phenylalanine pH and temperature not specified in the publication Micrococcus percitreus