Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli BL21 (DE3)-Transetta cells | Azumapecten farreri |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
63380 | - |
x * 63380, calculated from amino acid sequence | Azumapecten farreri |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Azumapecten farreri | F8QPW5 | - |
- |
Purification (Comment) | Organism |
---|---|
Ni2+ chelating Sepharose column chromatography | Azumapecten farreri |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adductor muscle | - |
Azumapecten farreri | - |
gill | - |
Azumapecten farreri | - |
gonad | - |
Azumapecten farreri | - |
hemocyte | - |
Azumapecten farreri | - |
hepatopancreas | highest expression of DDC mRNA | Azumapecten farreri | - |
kidney | - |
Azumapecten farreri | - |
mantle | - |
Azumapecten farreri | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Dopa | - |
Azumapecten farreri | dopamine + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 63380, calculated from amino acid sequence | Azumapecten farreri |
Synonyms | Comment | Organism |
---|---|---|
AADC | - |
Azumapecten farreri |
DDC | - |
Azumapecten farreri |
DOPA decarboxylase | - |
Azumapecten farreri |
L-DOPA decarboxylase | - |
Azumapecten farreri |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Azumapecten farreri |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Azumapecten farreri | calculated from amino acid sequence | - |
6.1 |
Organism | Comment | Expression |
---|---|---|
Azumapecten farreri | after treatment with lipopolysaccharide stimulation, the mRNA expression level of DDC in hemocytes increases 5.5fold at 3 h and 9.8fold at 12 h and then recovers to the baseline level | up |
General Information | Comment | Organism |
---|---|---|
physiological function | DDC modulates the immune responses such as hemocytes encapsulation as well as the reactive oxygen species level through its catalytic activity, functioning as an indispensable immunomodulating enzyme in the neuroendocrine-immune regulatory network of mollusk | Azumapecten farreri |