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Literature summary for 4.1.1.28 extracted from
- The molecular mechanisms of cuticular melanization: the ecdysone cascade leading to dopa decarboxylase expression in Manduca sexta (2009), Insect Biochem. Mol. Biol., 39, 245-253.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Manduca sexta | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epidermis | - |
Manduca sexta | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Dopa | - |
Manduca sexta | dopamine + CO2 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DDC | - |
Manduca sexta |
| DOPA decarboxylase | - |
Manduca sexta |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Manduca sexta | |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Manduca sexta | both 20-hydroxyecdysone and juvenile hormone regulate DDC expression in the epidermis | down |
| Manduca sexta | ecdysone cascades regulate DDC expression in the epidermis | up |
General Information
| General Information | Comment | Organism |
|---|---|---|
| physiological function | dopa decarboxylase is necessary for insect cuticular melanization | Manduca sexta |
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