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Literature summary for 4.1.1.23 extracted from

  • Cui, W.; DeWitt, J.G.; Miller, S.M.; Wu, W.
    No metal cofactor in orotidine 5'-monophosphate decarboxylase (1999), Biochem. Biophys. Res. Commun., 259, 133-135.
    View publication on PubMed
Search for more literature for 4.1.1.23

Inhibitors

Inhibitors Comment Organism Structure
additional information not inhibited by zinc-chelating agents, e.g. EDTA Saccharomyces cerevisiae

Metals/Ions

Metals/Ions Comment Organism Structure
additional information no metal cofactor, e.g. Zn2+ or other transition metal ions Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Orotidine 5'-phosphate Saccharomyces cerevisiae catalyzes the final step of de novo pyrimidine nucleotide biosynthesis UMP + CO2
-
 ?
Orotidine 5'-phosphate Saccharomyces cerevisiae BJ5464 catalyzes the final step of de novo pyrimidine nucleotide biosynthesis UMP + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae BJ5464
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Saccharomyces cerevisiae

Reaction

Reaction Comment Organism Reaction ID
orotidine 5'-phosphate = UMP + CO2 mechanism Saccharomyces cerevisiae
a

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Orotidine 5'-phosphate mechanism Saccharomyces cerevisiae UMP + CO2
-
 ?
Orotidine 5'-phosphate catalyzes the final step of de novo pyrimidine nucleotide biosynthesis Saccharomyces cerevisiae UMP + CO2
-
 ?
Orotidine 5'-phosphate mechanism Saccharomyces cerevisiae BJ5464 UMP + CO2
-
 ?
Orotidine 5'-phosphate catalyzes the final step of de novo pyrimidine nucleotide biosynthesis Saccharomyces cerevisiae BJ5464 UMP + CO2
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
 assay at Saccharomyces cerevisiae

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6
-
 assay at Saccharomyces cerevisiae