General Stability | Organism |
---|---|
conversion of the monomer to higher molecular weight forms is associated with increased stability | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
potassium phosphate | - |
Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0006 | - |
orotidine 5'-phosphate | tetrameric enzyme form | Homo sapiens | |
0.003 | - |
orotidine 5'-phosphate | dimeric enzyme form | Homo sapiens | |
0.025 | - |
orotidine 5'-phosphate | monomeric enzyme form | Homo sapiens |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
62000 | - |
monomeric enzyme form, gel filtration | Homo sapiens |
115000 | - |
dimeric enzyme form, gel filtration | Homo sapiens |
250000 | - |
tetrameric enzyme form, gel filtration | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Purification (Comment) | Organism |
---|---|
partial | Homo sapiens |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
erythrocyte | - |
Homo sapiens | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.0017 | - |
- |
Homo sapiens |
Storage Stability | Organism |
---|---|
-15°C, storage of the high molecular weight forms in presence of 0.15 mM oxipurinol prevents the spontaneous dissociation which occures when these forms are stored in 50 mM potassium phosphate, pH 7.4 | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Orotidine 5'-phosphate | - |
Homo sapiens | UMP + CO2 | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
55 | - |
1 min: 60% loss of the activity of the monomeric form, 10% loss of activity of the tetrameric form | Homo sapiens |