Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine | Mus musculus | - |
histamine + CO2 | - |
? | |
L-histidine | Mus musculus BALB/c | - |
histamine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | P23738 | - |
- |
Mus musculus BALB/c | P23738 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
endomysium | - |
Mus musculus | - |
masseter | - |
Mus musculus | - |
additional information | immunostaining of HDC in murine skeletal muscle tissues, overview | Mus musculus | - |
pectoral muscle | - |
Mus musculus | - |
quadriceps | quadriceps femoris | Mus musculus | - |
skeletal muscle | masseter, pectoralis, and quadriceps femoris, in cells in the endomysium and around blood vessels, and also in some muscle fibers | Mus musculus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine | - |
Mus musculus | histamine + CO2 | - |
? | |
L-histidine | - |
Mus musculus BALB/c | histamine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HDC | - |
Mus musculus |
Organism | Comment | Expression |
---|---|---|
Mus musculus | induction of the histamine-forming enzyme histidine decarboxylase in skeletal muscles by prolonged muscular work, interleukin-1beta (IL-1beta) and TNF-alpha may cooperatively mediate this induction. IL-1beta increases HDC activity in all the muscles tested (masseter, pectoralis, and quadriceps femoris). HDC activity in these tissues peaks at around 5 h after the injection of IL-1beta (10 ng/g), injection of TNF-alpha (100 ng/g) also increases HDC activity in all of these muscles | up |