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Literature summary for 4.1.1.22 extracted from
- Induction of histidine decarboxylase in macrophages inhibited by the novel NF-kappaB inhibitor (-)-DHMEQ (2009), Biochem. Biophys. Res. Commun., 379, 379-383.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| C/EBPbeta | essential for the HDC induction | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | knockdown of the transcription factor C/EBPbeta by dehydroxymethylepoxyquinomicin reduces the HDC expression in lipopolysaccharide-treated cells | Mus musculus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| macrophage | - |
Mus musculus | - |
| RAW-264.7 cell | - |
Mus musculus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-histidine | - |
Mus musculus | histamine + CO2 | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| HDC | - |
Mus musculus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Mus musculus | |
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Release 2023.1 (January 2023)
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