Activating Compound | Comment | Organism | Structure |
---|---|---|---|
pyruvate | contains several functionally essential pyruvate residues, covalently bound through an amide linkage to a Phe residue of the peptide chain. The free carbonyl group of these pyruvate residues undergoes Schiff base formation with His as part of the catalytic process | Lactobacillus sp. |
Crystallization (Comment) | Organism |
---|---|
- |
Lactobacillus sp. |
General Stability | Organism |
---|---|
inactivated by freezing and thawing | Lactobacillus sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
imidazole | competitively inhibited | Lactobacillus sp. | |
KCN | non-competitive | Lactobacillus sp. | |
PCMB | - |
Lactobacillus sp. |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
9000 | - |
x * 9000 + x * 29700, the larger subunit contains a pyruvate residue | Lactobacillus sp. |
29700 | - |
x * 9000 + x * 29700, the larger subunit contains a pyruvate residue | Lactobacillus sp. |
190000 | - |
- |
Lactobacillus sp. |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Lactobacillus sp. | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Lactobacillus sp. |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
69 | - |
- |
Lactobacillus sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
1-Methylhistidine | very poor substrate | Lactobacillus sp. | 1-Methylhistamine | - |
? | |
2-Thiolhistidine | very poor substrate | Lactobacillus sp. | 1-Thiolhistamine | - |
? | |
3-Methylhistidine | very poor substrate | Lactobacillus sp. | 2-Methylhistamine | - |
? | |
beta-(1,2,4-Triazole-3)-Ala | very poor substrate | Lactobacillus sp. | ? | - |
? | |
beta-(Pyridyl-2)-Ala | very poor substrate | Lactobacillus sp. | ? | - |
? | |
beta-(Thiazole-2)-Ala | very poor substrate | Lactobacillus sp. | ? | - |
? | |
L-His | - |
Lactobacillus sp. | Histamine + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 9000 + x * 29700, the larger subunit contains a pyruvate residue | Lactobacillus sp. |