Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Methanocaldococcus jannaschii |
Crystallization (Comment) | Organism |
---|---|
co-crystals of DAPDC and azelaic acid and L-lysine at 2.6 A and 2.0 A resolution, respectively, hanging drop vapor-diffusion, 12% polyethylene glycol 6000, 100 mm Tris-Cl, pH 8.0, 20 mM MgCl2 and 10 mM L-lysine | Methanocaldococcus jannaschii |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
1,5-Diaminopentane | - |
Methanocaldococcus jannaschii | |
1,6-diaminohexane | - |
Methanocaldococcus jannaschii | |
1,7-Diaminoheptane | - |
Methanocaldococcus jannaschii | |
adipic acid | - |
Methanocaldococcus jannaschii | |
azelaic acid | - |
Methanocaldococcus jannaschii | |
caproic acid | - |
Methanocaldococcus jannaschii |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
50000 | - |
x * 50000, mass spectrometry | Methanocaldococcus jannaschii |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
meso-2,6-Diaminoheptanedioate | Methanocaldococcus jannaschii | last step in L-lysine biosynthesis | L-Lysine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Methanocaldococcus jannaschii | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant DAPDC | Methanocaldococcus jannaschii |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
meso-2,6-Diaminoheptanedioate | - |
Methanocaldococcus jannaschii | L-Lysine + CO2 | - |
? | |
meso-2,6-Diaminoheptanedioate | last step in L-lysine biosynthesis | Methanocaldococcus jannaschii | L-Lysine + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 50000, mass spectrometry | Methanocaldococcus jannaschii |
Synonyms | Comment | Organism |
---|---|---|
DAPDC | - |
Methanocaldococcus jannaschii |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.0024 | - |
1,6-diaminohexane | - |
Methanocaldococcus jannaschii | |
0.0025 | - |
1,7-Diaminoheptane | - |
Methanocaldococcus jannaschii | |
0.004 | - |
1,5-Diaminopentane | - |
Methanocaldococcus jannaschii | |
0.089 | - |
azelaic acid | - |
Methanocaldococcus jannaschii | |
0.13 | - |
adipic acid | - |
Methanocaldococcus jannaschii | |
0.21 | - |
caproic acid | - |
Methanocaldococcus jannaschii |