Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | chronic treatment, over 21 days, with glucocorticoids, via dexamethasone, alters endogenous agmatine and arginine decarboxylase levels in the brain, reversible by exogenous agmatine, overview | Rattus norvegicus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine | Rattus norvegicus | the enzyme is the enzyme essential for agmatine synthesis, chronic treatment with glucocorticoids alters rat hippocampal and prefrontal cortical morphology in parallel with endogenous agmatine and arginine decarboxylase levels, neuroprotective effect of agmatine on dexamethasone-induced neuronal damage in brain areas, overview | agmatine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Harlan Sprague-Dawley rats | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | - |
Rattus norvegicus | - |
hippocampus | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
quantitative determination of agmatine levels in the brain | Rattus norvegicus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine | - |
Rattus norvegicus | agmatine + CO2 | - |
? | |
L-arginine | the enzyme is the enzyme essential for agmatine synthesis, chronic treatment with glucocorticoids alters rat hippocampal and prefrontal cortical morphology in parallel with endogenous agmatine and arginine decarboxylase levels, neuroprotective effect of agmatine on dexamethasone-induced neuronal damage in brain areas, overview | Rattus norvegicus | agmatine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ADC | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Rattus norvegicus |