Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | profiles of the steady-state accumulation of Synechocystis ADC transcripts and ADC specific activities under various environmental conditions, e.g. photoheterotrophy, high temperature and high light conditions activate enzyme expression, overview | Synechocystis sp. |
Cloned (Comment) | Organism |
---|---|
profiles of the steady-state accumulation of Synechocystis ADC transcripts and ADC specific activities under various environmental conditions, overview | Synechocystis sp. |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | profiles of the steady-state accumulation of Synechocystis ADC transcripts and ADC specific activities under various environmental conditions, e.g. darkness and cold reduce enzyme expression, overview | Synechocystis sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine | Synechocystis sp. | key enzyme in the biosynthesis of polyamines, key enzyme in the biosynthesis of putrescine, plays a role in salt stress response, high temperature and glucose treatment causes an increase in the specific activity, the specific activity is reduced by iron deficiency | agmatine + CO2 | - |
? | |
L-arginine | Synechocystis sp. | the first enzyme in the alternative route to putrescine in the polyamine biosynthesis pathway in bacteria and plants, posttranslational regulation involving a putative extra domain, modelling, overview | agmatine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Synechocystis sp. | - |
PCC 6803 | - |
Synechocystis sp. | - |
strain PCC 6803, two genes encoding the enzyme | - |
Synechocystis sp. | P74576 | isoform ADC1 | - |
Posttranslational Modification | Comment | Organism |
---|---|---|
side-chain modification | two symmetric inter-subunit disulfide bonds seem to stabilize the dimeric structure of arginine decarboxylase | Synechocystis sp. |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | profiles of the steady-state accumulation of Synechocystis ADC transcripts and ADC specific activities under various environmental conditions | Synechocystis sp. | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
profiles of the steady-state accumulation of Synechocystis ADC transcripts and ADC specific activities under various environmental conditions, overview | Synechocystis sp. |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-arginine | - |
Synechocystis sp. | agmatine + CO2 | - |
? | |
L-arginine | key enzyme in the biosynthesis of polyamines, key enzyme in the biosynthesis of putrescine, plays a role in salt stress response, high temperature and glucose treatment causes an increase in the specific activity, the specific activity is reduced by iron deficiency | Synechocystis sp. | agmatine + CO2 | - |
? | |
L-arginine | the first enzyme in the alternative route to putrescine in the polyamine biosynthesis pathway in bacteria and plants, posttranslational regulation involving a putative extra domain, modelling, overview | Synechocystis sp. | agmatine + CO2 | - |
? | |
L-arginine | effects of various types of short-term stresses on the transcript amount and specific activity of the enzyme, overview | Synechocystis sp. | agmatine + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
dimer | stabilized by two inter-subunit disulfide bonds, structural modeling | Synechocystis sp. |
More | Synechocystis ADCs have a putative extra domain, which might be involved in the posttranslational regulation of ADC activity, structural modeling, overview | Synechocystis sp. |
Synonyms | Comment | Organism |
---|---|---|
ADC | - |
Synechocystis sp. |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | conserved binding site structure | Synechocystis sp. | |
pyridoxal 5'-phosphate | the pyridoxal 5'-phosphate-binding domain is linked to the C-terminal domain by the N-terminus | Synechocystis sp. |
Organism | Comment | Expression |
---|---|---|
Synechocystis sp. | steady-state accumulation of arginine decarboxylase transcripts and its specific activity are unaffected by dark incubation | additional information |
Synechocystis sp. | salt stress clearly results in an increased steady-state transcript accumulation even though the specific activity shows no apparent change | up |