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Literature summary for 4.1.1.17 extracted from

  • Marcora, M.S.; Cejas, S.; Gonzalez, N.S.; Carrillo, C.; Algranati, I.D.
    Polyamine biosynthesis in Phytomonas: Biochemical characterization of a very unstable ornithine decarboxylase (2010), Int. J. Parasitol., 40, 1389-1394.
    View publication on PubMed

General Stability

General Stability Organism
Phytomonas ODC can be markedly stabilized by 0.05 mM MG-132 Phytomonas sp.

Inhibitors

Inhibitors Comment Organism Structure
alpha-difluoromethylornithine specific inhibitor Phytomonas sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.4
-
L-ornithine apparent value, at 37°C Phytomonas sp.

Organic Solvent Stability

Organic Solvent Comment Organism
DMSO about 40% specific activity after 0.5 h of DMSO treatment Phytomonas sp.

Organism

Organism UniProt Comment Textmining
Phytomonas sp.
-
-
-
Phytomonas sp. Jma
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
-
Phytomonas sp. putrescine + CO2
-
?
L-ornithine
-
Phytomonas sp. Jma putrescine + CO2
-
?

Synonyms

Synonyms Comment Organism
ODC
-
Phytomonas sp.

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
45
-
-
Phytomonas sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.4
-
-
Phytomonas sp.

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate required for maximum activity Phytomonas sp.

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.2
-
at 37°C Phytomonas sp. alpha-difluoromethylornithine