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Literature summary for 4.1.1.17 extracted from

  • Ehrnstroem, R.A.; Bjursten, L.M.; Ljungberg, O.; Veress, B.; Haglund, M.E.; Lindstroem, C.G.; Andersson, T.
    Dietary supplementation with carbonate increases expression of ornithine decarboxylase and proliferation in gastric mucosa in a rat model of gastric cancer (2008), Int. J. Cancer, 122, 727-733.
    View publication on PubMed
Search for more literature for 4.1.1.17

Activating Compound

Activating Compound Comment Organism Structure
additional information carbonate ions increase the ODC enzyme expression Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Rattus norvegicus ornithine decarboxylase is a cancer related protein. ODC is the key enzyme in polyamine synthesis and a regulator of cell proliferation. In gastric mucosal inflammation, induced by NaHCO3 feeding, ODC expression and activity is increased correlated to enhanced cell proliferation, overview ?
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Organism

Organism UniProt Comment Textmining
Rattus norvegicus
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 male Wistar rats
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Source Tissue

Source Tissue Comment Organism Textmining
gastric cancer cell
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 Rattus norvegicus
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gastric mucosa positive nuclei in the junction Rattus norvegicus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information ornithine decarboxylase is a cancer related protein. ODC is the key enzyme in polyamine synthesis and a regulator of cell proliferation. In gastric mucosal inflammation, induced by NaHCO3 feeding, ODC expression and activity is increased correlated to enhanced cell proliferation, overview Rattus norvegicus ?
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 ?

Synonyms

Synonyms Comment Organism
ODC
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 Rattus norvegicus