Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Trypanosoma brucei |
Protein Variants | Comment | Organism |
---|---|---|
K69A | ODC copurifies with amines, e.g. putrescine, similar affinity for pyridoxal 5'-phosphate as wild-type | Trypanosoma brucei |
K69R | 0.02% of wild-type activity, binds diamines and amino acids with higher affinity than wild-type ODC | Trypanosoma brucei |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.18 | - |
L-ornithine | K69R mutant | Trypanosoma brucei | |
0.4 | - |
L-ornithine | - |
Trypanosoma brucei |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine | Trypanosoma brucei | - |
putrescine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Trypanosoma brucei | - |
- |
- |
Purification (Comment) | Organism |
---|---|
recombinant ODC | Trypanosoma brucei |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-ornithine | - |
Trypanosoma brucei | putrescine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ODC | - |
Trypanosoma brucei |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
15 | - |
L-ornithine | - |
Trypanosoma brucei |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Trypanosoma brucei |