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Literature summary for 4.1.1.17 extracted from

  • Eichler, W.
    Properties of purified L-ornithine decarboxylase (EC 4.1.1.17) from Tetrahymena thermophila (1989), J. Protozool., 36, 577-582.
    View publication on PubMed
Search for more literature for 4.1.1.17

Activating Compound

Activating Compound Comment Organism Structure
DNA stimulates Tetrahymena thermophila
heparin stimulates Tetrahymena thermophila
RNA stimulates Tetrahymena thermophila

Inhibitors

Inhibitors Comment Organism Structure
alpha-DL-difluoromethylornithine
-
 Tetrahymena thermophila
putrescine slight Tetrahymena thermophila

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.11
-
 L-Orn
-
 Tetrahymena thermophila
0.17
-
 L-Orn
-
 Tetrahymena thermophila

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
68000
-
 gel filtration Tetrahymena thermophila

Organism

Organism UniProt Comment Textmining
Tetrahymena thermophila
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Tetrahymena thermophila

Storage Stability

Storage Stability Organism
stable at 0°C Tetrahymena thermophila

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Orn
-
 Tetrahymena thermophila Putrescine + CO2
-
 ?

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
37
-
 1 h, 14% loss of activity Tetrahymena thermophila

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6 7
-
 Tetrahymena thermophila

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate Km: 0.00023 mM Tetrahymena thermophila