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Literature summary for 4.1.1.17 extracted from

  • Yarlett, N.; Goldberg, B.; Moharrami, M.A.; Bacchi, C.J.
    Trichomonas vaginalis: characterization of ornithine decarboxylase (1993), Biochem. J., 293, 487-493.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.17

Inhibitors

Inhibitors Comment Organism Structure
alpha-DL-difluoromethylornithine
-
 Trichomonas vaginalis
Carbamoyl phosphate
-
 Trichomonas vaginalis
Lys relatively ineffective Trichomonas vaginalis
Orn inhibition of Lys decarboxylation Trichomonas vaginalis
putrescine
-
 Trichomonas vaginalis
spermidine no inhibition Trichomonas vaginalis

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.091
-
 Lys
-
 Trichomonas vaginalis
0.1
-
 Arg
-
 Trichomonas vaginalis
0.109
-
 L-Orn
-
 Trichomonas vaginalis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
55000
-
 4 * 55000, SDS-PAGE Trichomonas vaginalis
210000
-
 gel filtration Trichomonas vaginalis

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Orn Trichomonas vaginalis key enzyme in polyamine metabolism ?
-
 ?

Organism

Organism UniProt Comment Textmining
Trichomonas vaginalis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Trichomonas vaginalis

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.859
-
-
 Trichomonas vaginalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Arg 0.1% of the activity with L-Orn Trichomonas vaginalis 1-Amino-4-guanidinobutane
-
 ?
L-Lys at 1.0% of the activity with Orn Trichomonas vaginalis 1,5-diaminopentane + CO2
-
 ?
L-Orn
-
 Trichomonas vaginalis Putrescine + CO2
-
 ?
L-Orn key enzyme in polyamine metabolism Trichomonas vaginalis ?
-
 ?

Subunits

Subunits Comment Organism
tetramer 4 * 55000, SDS-PAGE Trichomonas vaginalis

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
-
 Trichomonas vaginalis

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
 Trichomonas vaginalis

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate required Trichomonas vaginalis