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Literature summary for 4.1.1.17 extracted from

  • Hietala, O.A.; Yum, K.Y.; Pilon, J.; O'Donnell, K.; Holroyde, C.P.; Kline, I.; Reichard, G.A.; Litwin, S.; Gilmour, S.K.; O'Brien, T.G.
    Properties of ornithine decarboxylase in human colorectal adenocarcinomas (1990), Cancer Res., 50, 2088-2094.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Orn Homo sapiens alteration in the key enzyme in the growth-associated pathway of polyamine biosynthesis may play a role in colon tumor progression ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
colonic mucosa
-
 Homo sapiens
-
colorectal adenocarcinoma cell multiple enzyme forms in tumor cells Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Orn
-
 Homo sapiens Putrescine + CO2
-
 ?
L-Orn alteration in the key enzyme in the growth-associated pathway of polyamine biosynthesis may play a role in colon tumor progression Homo sapiens ?
-
 ?