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Literature summary for 4.1.1.15 extracted from

  • Buttenschoen, H.N.; Lauritsen, M.B.; Daoud, A.E.; Hollegaard, M.; Jorgensen, M.; Tvedegaard, K.; Hougaard, D.; Boerglum, A.; Thorsen, P.; Mors, O.
    A population-based association study of glutamate decarboxylase 1 as a candidate gene for autism (2009), J. Neural Transm., 116, 381-388.
    View publication on PubMed
Search for more literature for 4.1.1.15

Cloned(Commentary)

Cloned (Comment) Organism
gene GAD1, genomic organization, the gene located within chromosome 2q31 encodes the isozyme GAD67 Homo sapiens

Protein Variants

Protein Variants Comment Organism
additional information detection of a naturally occuring mutant with nine single nucleotide polymorphisms spanning the promoter region of the GAD1 gene to the 3'-UTR Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-glutamate Homo sapiens
-
 4-aminobutanoate + CO2
-
 ?
additional information Homo sapiens GAD1 might be the susceptibility gene or another one being the susceptibility gene for autism, located on chromosome 2q31 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 gene GAD1 encodes the isozyme GAD67
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-glutamate
-
 Homo sapiens 4-aminobutanoate + CO2
-
 ?
additional information GAD1 might be the susceptibility gene or another one being the susceptibility gene for autism, located on chromosome 2q31 Homo sapiens ?
-
 ?

Synonyms

Synonyms Comment Organism
GAD67
-
 Homo sapiens
glutamate decarboxylase 1
-
 Homo sapiens