Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Ser | acticates liver enzyme, competitively inhibits kidney and brain enzyme | Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Ala | liver enzyme | Rattus norvegicus | |
Aminooxyacetate | - |
Rattus norvegicus | |
beta-Ala | liver enzyme | Rattus norvegicus | |
Cys | liver enzyme | Rattus norvegicus | |
Gln | liver enzyme | Rattus norvegicus | |
Glu | liver enzyme | Rattus norvegicus | |
Ser | activates liver enzyme, competitively inhibits kidney and brain enzyme | Rattus norvegicus | |
Val | weak, liver enzyme | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
1.3 | - |
L-Asp | brain enzyme | Rattus norvegicus | |
3.5 | - |
L-Asp | liver and kidney enzyme | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | highest activity in the cortex, lowest activity in the striatum and hippocampus | Rattus norvegicus | - |
kidney | - |
Rattus norvegicus | - |
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-Asp | - |
Rattus norvegicus | L-Ala + CO2 | - |
? |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.1 | 7.4 | - |
Rattus norvegicus |
7.4 | - |
- |
Rattus norvegicus |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5.7 | 8.1 | about 60% of maximal activity at pH 5.7 and pH 8.1 | Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | firmly bound cofactor | Rattus norvegicus |