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Literature summary for 4.1.1.112 extracted from

  • Granjon, T.; Maniti, O.; Auchli, Y.; Dahinden, P.; Buchet, R.; Marcillat, O.; Dimroth, P.
    Structure-function relations in oxaloacetate decarboxylase complex. Fluorescence and infrared approaches to monitor oxomalonate and Na+ binding effect (2010), PLoS ONE, 5, e10935.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 4.1.1.112

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli C43(DE3) cells Vibrio cholerae serotype O1

Inhibitors

Inhibitors Comment Organism Structure
NaCl OAD tertiary structure is sensitive to the presence of NaCl Vibrio cholerae serotype O1
oxomalonate competitive inhibitor of OAD with respect to oxaloacetate Vibrio cholerae serotype O1

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
 Vibrio cholerae serotype O1 16020
-

Metals/Ions

Metals/Ions Comment Organism Structure
Zn2+ the gamma subunit contains zinc Vibrio cholerae serotype O1

Organism

Organism UniProt Comment Textmining
Vibrio cholerae serotype O1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
avidin-Sepharose column chromatography Vibrio cholerae serotype O1

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Oxaloacetate
-
 Vibrio cholerae serotype O1 Pyruvate + CO2
-
 ?

Subunits

Subunits Comment Organism
heterotrimer
-
 Vibrio cholerae serotype O1

Synonyms

Synonyms Comment Organism
OAD
-
 Vibrio cholerae serotype O1

General Information

General Information Comment Organism
metabolism OAD of Vibrio cholerae catalyses a key step in citrate fermentation, converting the chemical energy of the decarboxylation reaction into an electrochemical gradient of Na+ ions across the membrane, which drives endergonic membrane reactions such as ATP synthesis, transport and motility Vibrio cholerae serotype O1