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Literature summary for 4.1.1.112 extracted from
- Properties of oxaloacetate decarboxylase from veillonella parvula (1982), J. Bacteriol., 150, 1252-1258.
General Stability
| General Stability | Organism |
|---|---|
| buffer-dependent, mercaptoethanol stabilises | Veillonella parvula |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ATP | carboxylation competitively inhibited, decarboxylation non-competitively, Ki: 2.2 mM, possibly involved in regulation | Veillonella parvula |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.06 | - |
oxaloacetate | - |
Veillonella parvula | |
| 1 | - |
CO2 | - |
Veillonella parvula | |
| 3.3 | - |
pyruvate | - |
Veillonella parvula | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required, decarboxylation Km: 0.17 mM, carboxylation Km: 1.85 mM | Veillonella parvula | |
| Mn2+ | required | Veillonella parvula | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| oxaloacetate | Veillonella parvula | - |
? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Veillonella parvula | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Veillonella parvula |
Reaction
| Reaction | Comment | Organism | Reaction ID |
|---|---|---|---|
| oxaloacetate = pyruvate + CO2 | Keq: 0.00213 1/mM, decarboxylation favored | Veillonella parvula | |
| oxaloacetate = pyruvate + CO2 | pyruvate + CO2 = oxaloacetae | Veillonella parvula |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 18.9 | - |
- |
Veillonella parvula |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, phosphate buffer or arsenate buffer, pH 7, with mercaptoethanol, N2-atmosphere, 2 months | Veillonella parvula |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Oxaloacetate | - |
Veillonella parvula | Pyruvate + CO2 | - |
? | |
| oxaloacetate | - |
Veillonella parvula | ? | - |
? | |
| Pyruvate + CO2 | - |
Veillonella parvula | Oxaloacetate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
enzyme assay at | Veillonella parvula |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
enzyme assay at | Veillonella parvula |
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