Activating Compound | Comment | Organism | Structure |
---|---|---|---|
PanZ | the enzyme requires activation by PanZ to be posttranslationally cleaved | Escherichia coli |
Application | Comment | Organism |
---|---|---|
synthesis | the enzyme is used for industrial production of beta-alanine from L-aspartate | Corynebacterium glutamicum |
synthesis | the enzyme is used for industrial production of beta-alanine from L-aspartate | Escherichia coli |
synthesis | the enzyme is used for industrial production of beta-alanine from L-aspartate | Bacillus subtilis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate | Corynebacterium glutamicum | - |
beta-alanine + CO2 | - |
? | |
L-aspartate | Escherichia coli | - |
beta-alanine + CO2 | - |
? | |
L-aspartate | Bacillus subtilis | - |
beta-alanine + CO2 | - |
? | |
L-aspartate | Bacillus subtilis 168 | - |
beta-alanine + CO2 | - |
? | |
L-aspartate | Corynebacterium glutamicum DSM 20300 | - |
beta-alanine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | P52999 | - |
- |
Bacillus subtilis 168 | P52999 | - |
- |
Corynebacterium glutamicum | Q9X4N0 | - |
- |
Corynebacterium glutamicum DSM 20300 | Q9X4N0 | - |
- |
Escherichia coli | P0A790 | - |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | the enzyme performs self-cleavage posttranslationally | Corynebacterium glutamicum |
proteolytic modification | the enzyme performs self-cleavage posttranslationally | Bacillus subtilis |
proteolytic modification | the enzyme requires activation by PanZ to be posttranslationally cleaved | Escherichia coli |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.98 | - |
pH and temperature not specified in the publication | Escherichia coli |
7.52 | - |
pH and temperature not specified in the publication | Corynebacterium glutamicum |
8.4 | - |
pH and temperature not specified in the publication | Bacillus subtilis |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-aspartate | - |
Corynebacterium glutamicum | beta-alanine + CO2 | - |
? | |
L-aspartate | - |
Escherichia coli | beta-alanine + CO2 | - |
? | |
L-aspartate | - |
Bacillus subtilis | beta-alanine + CO2 | - |
? | |
L-aspartate | - |
Bacillus subtilis 168 | beta-alanine + CO2 | - |
? | |
L-aspartate | - |
Corynebacterium glutamicum DSM 20300 | beta-alanine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
L-Aspartate-alpha-decarboxylase | - |
Corynebacterium glutamicum |
L-Aspartate-alpha-decarboxylase | - |
Escherichia coli |
L-Aspartate-alpha-decarboxylase | - |
Bacillus subtilis |
PanD | - |
Corynebacterium glutamicum |
PanD | - |
Escherichia coli |
PanD | - |
Bacillus subtilis |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
60 | - |
- |
Bacillus subtilis |
65 | - |
- |
Corynebacterium glutamicum |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
- |
Corynebacterium glutamicum |
6.5 | - |
- |
Bacillus subtilis |