Literature summary for 3.9.1.3 extracted from

Han, S.X.; Wang, L.J.; Zhao, J.; Zhang, Y.; Li, M.; Zhou, X.; Wang, J.; Zhu, Q.
14-kDa phosphohistidine phosphatase plays an important role in hepatocellular carcinoma cell proliferation (2012), Oncol. Lett., 4, 658-664.

Search for more literature for 3.9.1.3

Application

Application	Comment	Organism
medicine	the knockdown of enzyme expression by lentivirusdelivered siRNA is a therapeutic approach for the treatment of hepatocellular carcinoma	Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
14000	-	x * 14000, SDS-PAGE	Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
a [protein]-N-phospho-L-histidine + H2O	Homo sapiens	-	a [protein]-L-histidine + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
Hep-G2 cell	-	Homo sapiens	-
hepatocellular carcinoma cell	-	Homo sapiens	-
HL-7702 cell	-	Homo sapiens	-
SMMC-7721 cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
a [protein]-N-phospho-L-histidine + H2O	-	Homo sapiens	a [protein]-L-histidine + phosphate	-	?

Subunits

Subunits	Comment	Organism
?	x * 14000, SDS-PAGE	Homo sapiens

Synonyms

Synonyms	Comment	Organism
14-kDa phosphohistidine phosphatase	-	Homo sapiens
PHP14	-	Homo sapiens
PHPT1	-	Homo sapiens

General Information

General Information	Comment	Organism
malfunction	cell proliferation is inhibited and cell apoptosis is significantly increased following knockdown of 14kDa phosphohistidine phosphatase	Homo sapiens

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Release 2023.1 (January 2023)