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Literature summary for 3.9.1.3 extracted from

  • Klumpp, S.; Faber, D.; Fischer, D.; Litterscheid, S.; Krieglstein, J.
    Role of protein histidine phosphatase for viability of neuronal cells (2009), Brain Res., 1264, 7-12.
    View publication on PubMed
Search for more literature for 3.9.1.3

Cloned(Commentary)

Cloned (Comment) Organism
expressed in SH-SY5Y cells and in primary cultures of cortical neurons from embryonic (E19) rats Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
14000
-
 1 * 14000, SDS-PAGE Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
[ATP-citrate lyase]-N-phospho-L-histidine + H2O Homo sapiens
-
 [ATP-citrate lyase]-L-histidine + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
neuronal cell
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
[ATP-citrate lyase]-N-phospho-L-histidine + H2O
-
 Homo sapiens [ATP-citrate lyase]-L-histidine + phosphate
-
 ?

Subunits

Subunits Comment Organism
monomer 1 * 14000, SDS-PAGE Homo sapiens

Synonyms

Synonyms Comment Organism
PHP
-
 Homo sapiens
protein histidine phosphatase
-
 Homo sapiens

General Information

General Information Comment Organism
metabolism the enzyme reduces the activity of ATP-citrate lyase by dephosphorylation at His760 in the active site and, thus controls the main intermediate metabolism of the cell Homo sapiens