Literature summary for 3.8.1.7 extracted from

Crooks, G.P.; Xu, L.; Barkley, R.M.; Copley, S.D.
Exploration of possible mechanisms for 4-chlorobenzoyl CoA dehalogenase: evidence for an aryl-enzyme intermediate (1995), J. Am. Chem. Soc., 117, 10791-10798.

No PubMed abstract available

Organism

Organism	UniProt	Comment	Textmining
Arthrobacter sp.	-	-	-
Arthrobacter sp. 4-CB1	-	-	-

Reaction	Comment	Organism	Reaction ID
4-chlorobenzoyl-CoA + H2O = 4-hydroxybenzoyl CoA + chloride	formation of an aryl-enzyme intermediate that is converted to a hydroxamic acid upon attack by hydroxylamine. The dehalogenation appears to occur via an SNAr mechanism	Arthrobacter sp.	a

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Release 2023.1 (January 2023)