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Literature summary for 3.8.1.5 extracted from

  • Negri, A.; Marco, E.; Damborsky, J.; Gago, F.
    Stepwise dissection and visualization of the catalytic mechanism of haloalkane dehalogenase LinB using molecular dynamics simulations and computer graphics (2007), J. Mol. Graph. Model., 26, 643-651.
    View publication on PubMed

Application

Application Comment Organism
environmental protection LinB catalyses the conversion of a broad range of halogenated alkanes to their corresponding alcohols which makes it of particular interest for biomediation purposes Sphingobium indicum

Inhibitors

Inhibitors Comment Organism Structure
1,2-Dichloroethane competitive inhibitor Sphingobium indicum

Organism

Organism UniProt Comment Textmining
Sphingobium indicum A8CFB7 formerly, Sphingomonas paucimobilis
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.00072
-
1,2-dichloroethane Sphingobium indicum

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1,2-dibromoethane + H2O
-
Sphingobium indicum bromoethanol + bromide
-
?
1,2-dichloroethane + H2O
-
Sphingobium indicum ?
-
?
3-chloro-2-(chloromethyl)-1-propene + H2O
-
Sphingobium indicum ?
-
?
gamma-hexachlorocyclohexane + H2O
-
Sphingobium indicum ?
-
?

Synonyms

Synonyms Comment Organism
haloalkane dehalogenase
-
Sphingobium indicum
LinB
-
Sphingobium indicum