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Literature summary for 3.8.1.5 extracted from

  • Scholtz, R.; Leisinger, T.; Suter, F.; Cook, A.M.
    Characterization of 1-chlorohexane halidohydrolase, a dehalogenase of wide substrate range from an Arthrobacter sp (1987), J. Bacteriol., 169, 5016-5021.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.8.1.5

Inhibitors

Inhibitors Comment Organism Structure
4-hydroxymercuribenzoate weak Arthrobacter sp.
CuSO4
-
 Arthrobacter sp.
Phenylmercuriacetate
-
 Arthrobacter sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.02
-
 1-Bromopropane
-
 Arthrobacter sp.
0.04
-
 1-Chlorohexane
-
 Arthrobacter sp.
0.05
-
 1-Chloropentane
-
 Arthrobacter sp.
0.06
-
 1-Chlorobutane
-
 Arthrobacter sp.
0.08
-
 1-Iodopropane
-
 Arthrobacter sp.
0.15
-
 1-bromo-2-methylpropane
-
 Arthrobacter sp.
0.2
-
 1-iodoethane
-
 Arthrobacter sp.
1.2
-
 1-Chloropropane
-
 Arthrobacter sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
37000
-
 gel filtration, amino acid composition Arthrobacter sp.

Organism

Organism UniProt Comment Textmining
Arthrobacter sp.
-
-
-
Arthrobacter sp. HA1
-
-
-

Purification (Commentary)

Purification (Comment) Organism
strain HA1 Arthrobacter sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Arthrobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1-bromo-2-methylpropane + H2O
-
 Arthrobacter sp. 2-methylpropanol + bromide
-
 ?
1-bromopropane + H2O
-
 Arthrobacter sp. propanol + bromide
-
 ?
1-bromopropane + H2O
-
 Arthrobacter sp. HA1 propanol + bromide
-
 ?
1-chlorobutane + H2O
-
 Arthrobacter sp. 1-butanol + chloride
-
 ?
1-chlorohexane + H2O
-
 Arthrobacter sp. 1-hexanol + chloride
-
 ?
1-chloropentane + H2O
-
 Arthrobacter sp. 1-pentanol + chloride
-
 ?
1-chloropropane + H2O
-
 Arthrobacter sp. propanol + chloride
-
 ?
1-chloropropane + H2O
-
 Arthrobacter sp. HA1 propanol + chloride
-
 ?
1-iodoethane + H2O
-
 Arthrobacter sp. ethanol + iodide
-
 ?
1-iodopropane + H2O
-
 Arthrobacter sp. propanol + iodide
-
 ?
haloalkane + H2O overview Arthrobacter sp. alcohol + halide
-
 ?
haloalkane + H2O broad specificity Arthrobacter sp. alcohol + halide
-
 ?
haloalkane + H2O substrate range includes at least 50 halogenated compounds, 1-chloroalkanes C3 to C10, 1-bromoalkanes C1 to C9, 1-iodoalkanes C1 to C7, no 1-fluoroalkane, subterminally substituted, branched-chain and non-saturated haloalkanes, halogenated aromatic substrates, e.g. bromobenzene and benzyl bromide, several alpha,omega-dihaloalkanes are subject to double dehalogenation Arthrobacter sp. alcohol + halide
-
 ?
haloalkane + H2O overview Arthrobacter sp. HA1 alcohol + halide
-
 ?
haloalkane + H2O broad specificity Arthrobacter sp. HA1 alcohol + halide
-
 ?
haloalkane + H2O substrate range includes at least 50 halogenated compounds, 1-chloroalkanes C3 to C10, 1-bromoalkanes C1 to C9, 1-iodoalkanes C1 to C7, no 1-fluoroalkane, subterminally substituted, branched-chain and non-saturated haloalkanes, halogenated aromatic substrates, e.g. bromobenzene and benzyl bromide, several alpha,omega-dihaloalkanes are subject to double dehalogenation Arthrobacter sp. HA1 alcohol + halide
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
50
-
 about Arthrobacter sp.

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5 11
-
 Arthrobacter sp.