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Literature summary for 3.8.1.2 extracted from
- Carbon-halogen bond cleavage. 3. Studies on bacterial halidohydrolases (1968), J. Biol. Chem., 243, 428-434.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.3 | - |
Dichloroacetate | pH 9.4, 30°C | Pseudomonas sp. |  |
| 8 | - |
Monochloroacetate | pH 9.4, 30°C | Pseudomonas sp. | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-2-haloalkanoic acid + H2O | Pseudomonas sp. | - |
D-2-hydroxyalkanoic acid + halide | - |
? | |
| monochloroacetate + H2O | Pseudomonas sp. | - |
glycolate + HCl | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas sp. | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-2-haloacid + H2O | - |
Pseudomonas sp. | (R)-2-hydroxyacid + halide | - |
? | |
| dichloroacetate + H2O | - |
Pseudomonas sp. | ? | - |
? | |
| L-2-haloalkanoic acid + H2O | - |
Pseudomonas sp. | D-2-hydroxyalkanoic acid + halide | - |
? | |
| monochloroacetate + H2O | - |
Pseudomonas sp. | glycolate + HCl | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 9 | 9.4 | - |
Pseudomonas sp. |
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