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Literature summary for 3.7.1.5 extracted from

  • Watson, G.K.; Houghton, C.; Cain, R.B.
    Microbial metabolism of the pyridine ring. The metabolism of pyridine-3,4-diol (3,4-dihydroxypyridine) by Agrobacterium sp. (1974), Biochem. J., 140, 277-292.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.7.1.5

Activating Compound

Activating Compound Comment Organism Structure
CN- 62% activity increase at 0.1 mM Agrobacterium sp.
EDTA 32% activity increase at 1 mM Agrobacterium sp.

Inhibitors

Inhibitors Comment Organism Structure
Cu2+ 0.1 mM Agrobacterium sp.
Ni2+ 0.1 mM Agrobacterium sp.
Zn2+ 0.1 mM Agrobacterium sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.002
-
 3-formylpyruvate
-
 Agrobacterium sp.
0.007
-
 2,4-Dioxoheptanoate
-
 Agrobacterium sp.
0.007
-
 2,4-Dioxohexanoate
-
 Agrobacterium sp.
0.011
-
 2,4-Dioxovalerate
-
 Agrobacterium sp.

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
72000
-
 gel filtration Agrobacterium sp.

Organism

Organism UniProt Comment Textmining
Agrobacterium sp.
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,4-dioxoheptanoate + H2O
-
 Agrobacterium sp. ?
-
 ?
2,4-dioxohexanoate + H2O
-
 Agrobacterium sp. ?
-
 ?
2,4-dioxovalerate + H2O
-
 Agrobacterium sp. ?
-
 ?
3-formylpyruvate + H2O
-
 Agrobacterium sp. formate + pyruvate
-
 ir
acylpyruvate + H2O
-
 Agrobacterium sp. fatty acid + pyruvate
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8
-
-
 Agrobacterium sp.