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Literature summary for 3.7.1.3 extracted from

  • Tanizawa, K.; Soda, K.
    Comparison of inducible and constitutive kynureninases of Neurospora crassa (1979), J. Biochem., 85, 1367-1375.
    View publication on PubMed
Search for more literature for 3.7.1.3

Application

Application Comment Organism
medicine NAD+ biosynthesis Neurospora crassa
medicine tryptophan metabolism Neurospora crassa

Crystallization (Commentary)

Crystallization (Comment) Organism
-
 Neurospora crassa

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.034
-
 L-kynurenine constitutive enzyme Neurospora crassa
0.037
-
 L-3-hydroxykynurenine constitutive enzyme Neurospora crassa

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
110000
-
 constitutive and inducible enzyme, gel filtration Neurospora crassa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-hydroxy-L-kynurenine + H2O Neurospora crassa
-
 3-hydroxyanthranilate + L-Ala
-
 ?
L-kynurenine + H2O Neurospora crassa
-
 anthranilate + L-alanine
-
 ?

Organism

Organism UniProt Comment Textmining
Neurospora crassa
-
 constitutive and inducible enzyme
-

Purification (Commentary)

Purification (Comment) Organism
-
 Neurospora crassa

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-hydroxy-L-kynurenine + H2O
-
 Neurospora crassa 3-hydroxyanthranilate + L-alanine
-
 ?
3-hydroxy-L-kynurenine + H2O
-
 Neurospora crassa 3-hydroxyanthranilate + L-Ala
-
 ?
L-kynurenine + H2O
-
 Neurospora crassa anthranilate + L-alanine
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
8.5
-
 constitutive enzyme Neurospora crassa