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Literature summary for 3.7.1.2 extracted from
- Purification and properties of a diketo acid hydrolase from beef liver (1972), Biochemistry, 11, 2098-2102.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5,5'-dithiobis(2-nitrobenzoic acid) | 1 mM | Bos taurus |  |
| DFP | 1 mM | Bos taurus | |
| N-ethylmaleimide | 1 mM | Bos taurus | |
| p-hydroxymercuribenzoate | 1 mM | Bos taurus | |
| Trinitrobenzenesulfonic acid | 1 mM | Bos taurus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-fumarylacetoacetate + H2O | Bos taurus | - |
acetoacetate + fumarate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Bos taurus | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 36.3 | - |
- |
Bos taurus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-fumarylacetoacetate + H2O | - |
Bos taurus | acetoacetate + fumarate | - |
? | |
| acetopyruvic acid + H2O | - |
Bos taurus | acetic acid + pyruvic acid | - |
? | |
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