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Literature summary for 3.6.5.6 extracted from

  • Sage, C.R.; Dougherty, C.A.; Davis, A.S.; Burns, R.G.; Wilson, L.; Farrell, K.W.
    Site directed mutagenesis of putative GTP-binding sites of yeast beta-tubulin: Evidence that alpha-, beta-, and gamma-tubulins are atypical GTPases (1995), Biochemistry, 34, 7409-7419.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
beta-tubulin gene cloned and used for transformation Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Gallus gallus
-
GDP + phosphate
-
?
GTP + H2O Saccharomyces cerevisiae
-
GDP + phosphate
-
?
GTP + H2O Bos taurus
-
GDP + phosphate
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
bovine
-
Gallus gallus
-
chicken
-
Saccharomyces cerevisiae
-
yeast
-

Purification (Commentary)

Purification (Comment) Organism
purified to ca. 35% Saccharomyces cerevisiae

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Gallus gallus
-
brain
-
Bos taurus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
Gallus gallus GDP + phosphate
-
?
GTP + H2O
-
Saccharomyces cerevisiae GDP + phosphate
-
?
GTP + H2O
-
Bos taurus GDP + phosphate
-
?

Subunits

Subunits Comment Organism
dimer
-
Gallus gallus
dimer
-
Saccharomyces cerevisiae
dimer
-
Bos taurus

Synonyms

Synonyms Comment Organism
atypical GTPase
-
Saccharomyces cerevisiae