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Literature summary for 3.6.5.6 extracted from
- Mechanism of the microtubule GTPase reaction (1990), J. Biol. Chem., 265, 8935-8941.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| GDP | - |
Bos taurus |  |
| GDP | - |
Sus scrofa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 55000 | - |
SDS-PAGE | Sus scrofa |
| 101000 | - |
1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit | Sus scrofa |
| 106000 | - |
1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit | Sus scrofa |
| 115000 | - |
1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit | Sus scrofa |
| 128000 | - |
1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit | Sus scrofa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | Sus scrofa | - |
GDP + phosphate | - |
? | |
| GTP + H2O | Bos taurus | - |
GDP + phosphate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
| Sus scrofa | - |
pig | - |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
- |
Bos taurus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Sus scrofa | - |
| brain | - |
Bos taurus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Sus scrofa | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Bos taurus | GDP + phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 1 * 101000 + 1 * 106000 + 1 * 115000 + 1 * 128000, bands are probably tubulin dimers formed by cross-linking 2 alpha, 2 beta and an alpha and beta subunit | Sus scrofa |
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