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Literature summary for 3.6.5.5 extracted from
- Dynamin 2 regulates granule exocytosis during NK cell-mediated cytotoxicity (2008), J. Immunol., 181, 6995-7001.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dynasore | - |
Homo sapiens |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytolytic granule | dynamin 2 localizes with lytic granules and polarizes to the natural killer cell-target interface where it regulates the final fusion of lytic granules with the plasma membrane | Homo sapiens | 44194 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | dynamin 2 regulates granule exocytosis during natural killer cell-mediated cytotoxicity | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| natural killer cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | dynamin 2 regulates granule exocytosis during natural killer cell-mediated cytotoxicity | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DYN2 | - |
Homo sapiens |
| dynamin 2 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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