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Literature summary for 3.6.5.5 extracted from
- Cell division screens and dynamin (2008), Biochem. Soc. Trans., 36, 431-435.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi apparatus | isoform Dyn2aa is localized to plasma membrane and Golgi apparatus | Drosophila melanogaster | 5794 | - |
| Golgi apparatus | isoform Dyn2aa is localized to plasma membrane and Golgi apparatus | Caenorhabditis elegans | 5794 | - |
| plasma membrane | - |
Saccharomyces cerevisiae | 5886 | - |
| plasma membrane | - |
Danio rerio | 5886 | - |
| plasma membrane | isoform Dyn2ab is restricetd to the plasma membrane while isoform Dyn2aa is localized to plasma membrane and Golgi apparatus | Drosophila melanogaster | 5886 | - |
| plasma membrane | isoform Dyn2ab is restricetd to the plasma membrane while isoform Dyn2aa is localized to plasma membrane and Golgi apparatus | Caenorhabditis elegans | 5886 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Drosophila melanogaster | dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. | ? | - |
? |  |
| additional information | Caenorhabditis elegans | dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. | ? | - |
? | |
| additional information | Danio rerio | dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Caenorhabditis elegans | - |
- |
- |
| Caenorhabditis elegans | P39055 | - |
- |
| Danio rerio | - |
- |
- |
| Drosophila melanogaster | - |
- |
- |
| Saccharomyces cerevisiae | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| epithelial cell | - |
Drosophila melanogaster | - |
| epithelial cell | - |
Caenorhabditis elegans | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Drosophila melanogaster | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Saccharomyces cerevisiae | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Caenorhabditis elegans | GDP + phosphate | - |
? | |
| GTP + H2O | - |
Danio rerio | GDP + phosphate | - |
? | |
| additional information | dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. | Drosophila melanogaster | ? | - |
? | |
| additional information | dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. | Caenorhabditis elegans | ? | - |
? | |
| additional information | dynamin is a midbody protein associated with membrane remodelling that is also required for cytokinesis. Dynamin may also function as a link between the plasma membrane and actin filaments through interactions with proteins like Abp1, profilin, or cortacin. Alternatively, dynamin assembled on plasma membranes can act as structural component that organizes and stabilizes acti filaments at the furrow membrane, therefore being a platform from which the contractile ring forms. | Danio rerio | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Dyn1 | isoform | Drosophila melanogaster |
| Dyn1 | isoform | Danio rerio |
| Dyn1 | isoform | Caenorhabditis elegans |
| DYN2 | isoform | Drosophila melanogaster |
| DYN2 | isoform | Caenorhabditis elegans |
| DYN2 | isoform | Danio rerio |
| Dyn2aa | isoform | Drosophila melanogaster |
| Dyn2aa | isoform | Caenorhabditis elegans |
| Dyn2aa | isoform | Danio rerio |
| Dyn2ab | isoform | Drosophila melanogaster |
| Dyn2ab | isoform | Caenorhabditis elegans |
| Dyn2ab | isoform | Danio rerio |
| Dyn3 | isoform | Drosophila melanogaster |
| Dyn3 | isoform | Caenorhabditis elegans |
| Dyn3 | isoform | Danio rerio |
| dynamin 1 | isoform, originally identified as a microtubule-binding protein | Drosophila melanogaster |
| dynamin 1 | isoform, originally identified as a microtubule-binding protein | Danio rerio |
| dynamin 1 | isoform, originally identified as a microtubule-binding protein | Caenorhabditis elegans |
| dynamin 2 | isoform, plays a key role in endocytosis, actin dynamics, and membrane trafficking and is the only isoform that functions during cytokinesis | Drosophila melanogaster |
| dynamin 2 | isoform, plays a key role in endocytosis, actin dynamics, and membrane trafficking and is the only isoform that functions during cytokinesis | Caenorhabditis elegans |
| dynamin 2 | isoform, plays a key role in endocytosis, actin dynamics, and membrane trafficking and is the only isoform that functions during cytokinesis | Danio rerio |
| dynamin 3 | isoform | Drosophila melanogaster |
| dynamin 3 | isoform | Caenorhabditis elegans |
| dynamin 3 | isoform | Danio rerio |
| Vps1p | required for normal actin organization | Saccharomyces cerevisiae |
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