Protein Variants | Comment | Organism |
---|---|---|
additional information | mutations in shibire, the Drosophila dynamin, cause temperature-sensitive defects in endocytosis. The ts2 mutation, which occurs in the switch 2 region of dynamins GTPase domain, compromises GTP binding affinity. Three second-site suppressor mutations, one in the switch 1 region of the GTPase domain and two in the GTPase effector domain, dynamins putative GAP, fully rescue the shi ts2 defects in synaptic vesicle recycling | Drosophila sp. (in: flies) |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | Drosophila sp. (in: flies) | - |
GDP + phosphate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila sp. (in: flies) | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
GTP + H2O | - |
Drosophila sp. (in: flies) | GDP + phosphate | - |
? |