Literature summary for 3.6.5.5 extracted from

Rasmussen, R.K.; Rusak, J.; Price, G.; Robinson, P.J.; Simpson, R.J.; Dorow, D.S.
Mixed-lineage kinase 2-SH2 domain binds dynamin and greatly enhances activation of GTPase by phospholipid (1998), Biochem. J., 335, 119-124.

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Activating Compound

Activating Compound	Comment	Organism	Structure
Phospholipid	mixed-lineage kinase 2-SH2 domain binds dynamin and greatly enhances activation of GTPase by phospholipid	Homo sapiens
Phospholipid	mixed-lineage kinase 2-SH2 domain binds dynamin and greatly enhances activation of GTPase by phospholipid	Rattus norvegicus
Phospholipid	mixed-lineage kinase 2-SH2 domain binds dynamin and greatly enhances activation of GTPase by phospholipid	Ovis aries

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-
Ovis aries	-	-	-
Rattus norvegicus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
brain	-	Rattus norvegicus	-
brain	-	Ovis aries	-
breast adenocarcinoma cell	-	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + H2O	-	Homo sapiens	GDP + phosphate	-	?
GTP + H2O	-	Rattus norvegicus	GDP + phosphate	-	?
GTP + H2O	-	Ovis aries	GDP + phosphate	-	?

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Release 2023.1 (January 2023)