Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.6.5.4 extracted from

  • Ogg, S.C.; Barz, W.P.; Walter, P.
    A functional GTPase domain, but not its transmembrane domain, is required for function of the SRP receptor beta-subunit (1998), J. Cell Biol., 142, 341-354.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.6.5.4

Cloned(Commentary)

Cloned (Comment) Organism
-
 Saccharomyces cerevisiae

Protein Variants

Protein Variants Comment Organism
E157Q reduced affinity for GTP Saccharomyces cerevisiae
G90L mutant Saccharomyces cerevisiae
H91L reduced GTPase activity Saccharomyces cerevisiae
H91L/E157Q mutant Saccharomyces cerevisiae
H91L/N154A/E157A mutant Saccharomyces cerevisiae
H91L/N154I mutant Saccharomyces cerevisiae
K51A/T52A mutant Saccharomyces cerevisiae
K51A/T52A/E157Q mutant Saccharomyces cerevisiae
K51A/T52A/H91L mutant Saccharomyces cerevisiae
K51I reduced nucleotide affinity Saccharomyces cerevisiae
K51I/H91L mutant Saccharomyces cerevisiae
K51I/N154I mutant Saccharomyces cerevisiae
N154A/E157A mutant Saccharomyces cerevisiae
N154I impaired nucleotide exchange Saccharomyces cerevisiae
P46A/Q47A/N48A/DELTAS49 mutant Saccharomyces cerevisiae
S220A bypass requirement for GEF Saccharomyces cerevisiae
S49A reduced GTP hydrolysis Saccharomyces cerevisiae
T52N increased affinity for GEF, reduced affinity for GTP Saccharomyces cerevisiae
T66A prevents GTP-dependent interaction with GAP Saccharomyces cerevisiae

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
GTP + H2O Saccharomyces cerevisiae
-
 GDP + phosphate
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
 SR beta
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
GTP + H2O
-
 Saccharomyces cerevisiae GDP + phosphate
-
 ?