Literature summary for 3.6.5.3 extracted from

Maone, E.; Di Stefano, M.; Berardi, A.; Benelli, D.; Marzi, S.; La Teana, A.; Londei, P.
Functional analysis of the translation factor aIF2/5B in the thermophilic archaeon Sulfolobus solfataricus (2007), Mol. Microbiol., 65, 700-713.

Search for more literature for 3.6.5.3

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Saccharolobus solfataricus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
70000	-	x * 70000, His-tagged protein, SDS-PAGE	Saccharolobus solfataricus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
GTP + H2O	Saccharolobus solfataricus	ribosome-dependent GTPase strongly stimulates the binding of initiator tRNA to the ribosomes even in the absence of other factors	GDP + phosphate	-	?

Organism

Organism	UniProt	Comment	Textmining
Saccharolobus solfataricus	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Saccharolobus solfataricus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
GTP + H2O	ribosome-dependent GTPase strongly stimulates the binding of initiator tRNA to the ribosomes even in the absence of other factors	Saccharolobus solfataricus	GDP + phosphate	-	?
GTP + H2O	aIF2/5B enhances the translation of both leadered and leaderless mRNAs when expressed in a cell-free protein-synthesizing system	Saccharolobus solfataricus	GDP + phosphate	-	?

Subunits

Subunits	Comment	Organism
?	x * 70000, His-tagged protein, SDS-PAGE	Saccharolobus solfataricus

Synonyms

Synonyms	Comment	Organism
ribosome-dependent GTPase	-	Saccharolobus solfataricus
translation factor aIF2/5B	-	Saccharolobus solfataricus

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Release 2023.1 (January 2023)