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Literature summary for 3.6.5.3 extracted from
- Archaebacterial elongation factor 1 alpha carries the catalytic site for GTP hydrolysis (1994), J. Biol. Chem., 269, 20376-20379.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | polypeptide chain synthesis | Saccharolobus solfataricus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| GDP | - |
Saccharolobus solfataricus |  |
| ITP | - |
Saccharolobus solfataricus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.002 | 0.009 | GTP | depending on NaCl-concentration and temperature | Saccharolobus solfataricus | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Ba2+ | - |
Saccharolobus solfataricus | |
| Mg2+ | - |
Saccharolobus solfataricus | |
| Mn2+ | - |
Saccharolobus solfataricus | |
| Na+ | - |
Saccharolobus solfataricus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharolobus solfataricus | - |
strain ATCC 49255, elongation factor aEF-1alpha | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Saccharolobus solfataricus | GDP + phosphate | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 87 | - |
- |
Saccharolobus solfataricus |
Temperature Range [°C]
| Temperature Minimum [°C] | Temperature Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 60 | 93 | - |
Saccharolobus solfataricus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.5 | 10.5 | - |
Saccharolobus solfataricus |
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