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Literature summary for 3.6.5.2 extracted from
- Small GTPases in mechanosensitive regulation of endothelial barrier (2009), Microvasc. Res., 77, 46-52.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | Rac and Rho are also activated by mechanical stimulation like shear stress and cyclic stretch | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | Rho and Rac play a role in the regulation cytoskeletal remodeling and EC barrier regulation | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| endothelial cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? | |
| additional information | Rho and Rac play a role in the regulation cytoskeletal remodeling and EC barrier regulation | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Cdc42 | - |
Homo sapiens |
| Rac | - |
Homo sapiens |
| Rho | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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