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BRENDA support

Literature summary for 3.6.5.2 extracted from

  • Yoshida, T.; Clark, M.F.; Stern, P.H.
    The small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival (2009), J. Cell. Biochem., 106, 896-902.
    View publication on PubMedView publication on EuropePMC

Activating Compound

Activating Compound Comment Organism Structure
geranylgeranyl transferase I RhoA is activated by geranylgeranylation, which promotes its membrane anchoring, the geranylgeranyl transferase I inhibitor GGTI-2166to is used to inhibit geranylgeranylation Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
membrane
-
Mus musculus 16020
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus the small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
MC3T3-E1 cell
-
Mus musculus
-
osteoblast
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information the small GTPase RhoA is crucial for MC3T3-E1 osteoblastic cell survival Mus musculus ?
-
?

Synonyms

Synonyms Comment Organism
RhoA
-
Mus musculus