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Literature summary for 3.6.5.2 extracted from
- Thromboxane A2 receptors in prostate carcinoma: expression and its role in regulating cell motility via small GTPase Rho (2008), Cancer Res., 68, 115-121.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| U46619 | small GTPase RhoA is activated by the activation of functional receptors for thromboxane A2 like U46619 | Homo sapiens |  |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | RhoA may serve as intermediary for functional receptor for thromboxane A2-signaling axis to regulate tumor cell motility | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| PC-3 cell | - |
Homo sapiens | - |
| prostate cancer cell line | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| GTP + H2O | - |
Homo sapiens | GDP + phosphate | - |
? | |
| additional information | RhoA may serve as intermediary for functional receptor for thromboxane A2-signaling axis to regulate tumor cell motility | Homo sapiens | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| RhoA | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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