Literature summary for 3.6.5.2 extracted from

Ganter, M.T.; Roux, J.; Su, G.; Lynch, S.V.; Deutschman, C.S.; Weiss, Y.G.; Christiaans, S.C.; Myazawa, B.; Kipnis, E.; Wiener-Kronish, J.P.; Howard, M.; Pittet, J.F.
Role of small GTPases and alphavbeta5 integrin in Pseudomonas aeruginosa-induced increase in lung endothelial permeability (2009), Am. J. Respir. Cell Mol. Biol., 40, 108-118.

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Activating Compound

Activating Compound	Comment	Organism	Structure
additional information	exposure of confluent lung endothelial cell monolayers to wild type Pseudomonase aeruginosa strain PAK causes a significant increase in RhoA activity within 10 min	Bos taurus

Inhibitors

Inhibitors	Comment	Organism	Structure
additional information	exposure of confluent lung endothelial cell monolayers to wild type Pseudomonase aeruginosa strain PAK causes a significant decrease in Rac1 activity within 10 min	Bos taurus

Organism

Organism	UniProt	Comment	Textmining
Bos taurus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
lung endothelium	-	Bos taurus	-
pulmonary artery endothelial cell	macrovascular lung pulmonary artery endothelial cell	Bos taurus	-

Synonyms

Synonyms	Comment	Organism
Rac1	-	Bos taurus
RhoA	-	Bos taurus

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Release 2023.1 (January 2023)